Cheatography
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Action
Blocks factors XA and IIA in clotting cascade |
Indications
DOC in hospitalized patients because it doesn't have massive systemic effects |
BLACK BOX WARNING
Spinal block/epidural: hematoma or bleeding may occur causing permanent neurological damage |
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Drug Interactions
Anti-platelet drugs increase risk of thrombocytopenia |
Adverse Effects
Thrombocytopenia |
Toxicity (only if wrong dose is given) |
Neurological damage (r/t BBW) |
Administration
Route: SubQ |
Onset: 3-5 hours |
Half-life: 2-4 times longer than heparin |
Dosing: weight based --> predictable dose response |
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Nursing Implications
No required lab monitoring d/t predictable dose response |
Instruct patient on self-administration |
Monitor for bleeding |
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