Template for biochemical pathways Cheat Sheet by Verne89
A template that came handy for me to study Biochemistry: it requeires you to swicht from one format to another format. The process of analysing, then reconstructing is a good way to study anything.
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How the template works
The template for studying biochemical pathways works in real, physical paper: you get to use a pencil, rubber, and a ruler, and start sketching the pathway/s you need to study in the format provided here. When you analyze what you have and rebuild it in a different format, you're learning it.
Interpretation of the format provided
This is just a template for studying metabolic pathways, which uses the Krebs cycle to illustrate itself as an example. It uses alternate rows, as well as columns of input and columns of output. In the colored background rows we have the product of the previous reaction ( which is the reactive of the following reaction), next to the elements that are joined in the following reaction (INPUT), or those that are derived from the previous reaction (OUTPUT). The white rows contain the enzyme catalysing each reaction (with a number). These rows leave some space to the right to extra information, such as optimal conditions (pH, temperature, pressure ...), cofactors, the alpha of a reversible reaction (α), or whatever we want to study. As most biochemical reactions are reversible, those that are irreversible (in this case: 1, 3 and 4) are being put between brackets, because they are decisive.
Krebs Cycle - Template Example
Acetyl-CoA + H
( 1 )
HS-CoA + H+
( 3 )
HS-CoA + NAD+
NADH + CO
( 4 )
ADP + Pi
2 + NADH
Succinyl coenzyme A synthetase
ATP + HS-CoA
NADH + H+
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